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Leishmaniasis
Scientists at Federal University discuss research in leishmaniasis
March 25th, 2008
According to a study from Ouro Preto, Brazil, "A vaccine against canine visceral. leishmaniasis (CVL), comprising Leishmania braziliensis promastigote protein, sand fly gland extract (SGE) and saponin adjuvant, was evaluated in dog model, in order to analyse the immunogenicity of the candidate vaccine. The vaccine candidate elicited strong antigenicity in dogs in respect of specific SGE and Leishmania humoral. immune response." "The major saliva proteins recognized by serum from immunized dogs exhibited molecular weights of 35 and 45 kDa, and were related to the resistance pattern against Leishmania infection. Immunophenotypic analysis revealed increased circulating...
Source: TB & Outbreaks Week (2008-03-25)
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