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TB & Outbreaks Week

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Leishmaniasis



Study results from Federal University broaden understanding of leishmaniasis



March 25th, 2008

According to a study from Ouro Preto, Brazil, "While enlargement of popliteal lymph nodes (LN) is frequently described in canine visceral leishmaniasis (CVL), there are few histopathologic studies of lymph nodes during this chronic immunopathological condition. Besides a detailed histopathologic analysis, we have characterized the parasite load and major immunophenotypic features of the LN in Leishmania (Leishmania) chagasi-infected dogs."

"Our major histopathological findings highlight that hypertrophy/hyperplasia of LN cortical and medullary zones was the principal characteristic observed in asymptomatic dogs (AD), whereas atrophy of LN cortical zone was predominant...


Source: TB & Outbreaks Week (2008-03-25)

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