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Life Sciences
Research in the area of life sciences reported from T.C. Orlando and colleagues
March 25th, 2008
According to recent research from Sao Paulo, Brazil, "Leishmania (Sauroleishmania) tarentolae has biotechnological potential for use as live vaccine against visceral leishmaniasis and as a system for the over expression of eukaryotic proteins that possess accurate post-translational modifications. For both purposes, new systems for protein expression in this non-pathogenic protozoan are necessary." "The ribosomal RNA promoter proved to be a stronger transcription driver since its use yielded increased levels of recombinant protein in organisms of both genera Trypanosoma or Leishmania. We have evaluated heterologous expression systems using vectors with two different...
Source: TB & Outbreaks Week (2008-03-25)
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