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TB & Outbreaks Week

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DNA Research



Research from University of Zurich in the area of DNA research described



April 1st, 2008

According to a study from Zurich, Switzerland, "SMC (structural maintenance of chromosomes) proteins play fundamental roles in various aspects of chromosome organization and dynamics, including repair of DNA damage."

"Mutant strains of Mycobacterium smegmatis and Mycobacterium tuberculosis defective in SMC were constructed. Surprisingly, inactivation of smc did not result in recognizable phenotypes in hallmark assays characteristic for the function of these genes," wrote C. Guthlein and colleagues, University of Zurich.

The researchers concluded: "This is in contrast to data for smc null mutants in other species."

Guthlein and...


Source: TB & Outbreaks Week (2008-04-01)

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