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Bacillus Calmette-Guerin Vaccines
New Bacillus calmette-guerin vaccines study findings reported from A.O. Whelan and co-authors
April 1st, 2008
According to recent research from Addlestone, the United Kingdom, "Development of cattle vaccines against bovine tuberculosis is a GB research priority. Recently, it has been shown that formalin-killed Bacille Calmette-Guerin (BCG) delivered with the liposomal adjuvant NAX687 imparted significant protection against Mycobacterium bovis infection in the guinea pig aerosol infection model." "Extending these studies, we inoculated calves with live BCG, formalin-killed BCG and formalin-killed BCG formulated in NAX687. Live and killed BCG vaccine formulations induced primary effector T-cell populations comparably, both killed BCG formulations also induced potent humoral...
Source: TB & Outbreaks Week (2008-04-01)
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