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TB & Outbreaks Week

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Infectious Disease



Data on infectious disease discussed by researchers at University of Heidelberg



April 1st, 2008

"Adoptive transfer of CD8T cells has the potential to cure infectious or malignant diseases that are refractory to conventional chemotherapy. A practically important but still unanswered question is whether mixtures of protective CD8T cells with different epitope specificities mediate more efficient effector cell functions than do the monospecific individual CD8T cell populations," investigators in Mannheim, Germany report.

"In this study, we have addressed this issue for models of viral and bacterial infection. CD8T cell-mediated cytotoxicity in vitro and protection in vivo were assessed to test whether CD8T cell lines cooperate in target cell lysis and control of...


Source: TB & Outbreaks Week (2008-04-01)

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