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TB & Outbreaks Week

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Leishmaniasis



Research on leishmaniasis reported by J. Soto et al



April 1st, 2008

"Oral miltefosine (2.5 mg/kg/d for 28 days) was compared with intramuscular antimony (20 mg/kg/d for 20 days) in the treatment of cutaneous leishmaniasis caused by Leishmania braziliensis in Palos Blancos, Bolivia. The cure rates with 6 months of follow-up were statistically similar: 36 of 41 evaluable miltefosine patients (88%) versus 15 of 16 (94%) evaluable antimony patients," scientists writing in the American Journal of Tropical Medicine and Hygiene report.

"However, antimony cured more rapidly, because, by 1 month after therapy, 31 of 44 miltefosine patients (70%) compared with 16 of 16 antimony patients (100%) had achieved cure. The two conclusions from...


Source: TB & Outbreaks Week (2008-04-01)

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