Escherichia Coli Therapy
Researchers from McMaster University discuss findings in Escherichia coli therapy
Published in TB and Outbreaks Week, April 1st, 2008
New research, 'PagP activation in the outer membrane triggers R3 core oligosaccharide truncation in the cytoplasm of Escherichia coli O157:H7,' is the subject of a report. "The Escherichia coli outer membrane phospholipid:lipid A palmitoyltransferase PagP is normally a latent enzyme, but it can be directly activated in outer membranes by lipid redistribution associated with a breach in the permeability barrier. We now demonstrate that a lipid A myristate deficiency in an E. coli O157:H7 msbB mutant constitutively activates PagP in outer membranes," scientists in Hamilton, Canada report.
"The lipid A myristate deficiency is associated with hydrophobic...
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