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TB & Outbreaks Week

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Tuberculosis



New tuberculosis study results reported from University of Buenos Aires



April 8th, 2008

"The capability of Mycobacterium tuberculosis to rest in latency in the infected organism appears to be related to the disposal of cletoxification mechanisms, which converts the nitric oxide (NO) produced by macrophages during the initial growth infection stage into a nitrate anion. Such a reaction appears to be associated with the truncated hemoglobin N (trHbN)," scientists in Buenos Aires, Argentina report.

"Even though previous experimental and theoretical studies have examined the pathways used by NO and O-2 to access the heme cavity, the eggression pathway of the nitrate anion is still a challenging question. In this work we present results obtained by means of...


Source: TB & Outbreaks Week (2008-04-08)

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