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Bacterial Meningitis
Studies from T.H. Mogensen et al add new findings in the area of bacterial meningitis
April 8th, 2008
"Excessive inflammation contributes to the pathogenesis of bacterial meningitis, which remains a serious disease despite treatment with antibiotics. Therefore, anti-inflammatory drugs have important therapeutic potential, and clinical trials have revealed that early treatment with dexamethasone significantly reduces mortality and morbidity from bacterial meningitis," scientists in Aarhus, Denmark report. "Here we investigate the molecular mechanisms behind the inhibitory effect of dexamethasone upon the inflammatory responses evoked by Neisseria meningitidis and Streptococcus pneumoniae, two of the major causes of bacterial meningitis. The inflammatory cytokine response...
Source: TB & Outbreaks Week (2008-04-08)
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