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TB & Outbreaks Week

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Tuberculosis



Research findings from Army update understanding of tuberculosis



April 8th, 2008

"The diagnosis of tuberculosis remains among public health concerns due to shortcomings of the purified protein derivative (PPD). Recombinant truncated 38 kDa protein (rTPA38) of Mycobacterium tuberculosis was evaluated to screen new tuberculosis-specific tuberculin. 539 patients, 1133 healthy controls, and 55 guinea pigs were recruited to assess their sensitivity and specificity to rTPA38; 221 healthy controls, with negative responses to rTPA38 and PPD, were vaccinated with M. bovis BCG to determine their cross-reactions with M. bovis BCG," scientists writing in the Scandinavian Journal of Infectious Diseases report.

"The Mantoux technique was adopted to perform...


Source: TB & Outbreaks Week (2008-04-08)

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