Tuberculosis

Scientists at University of Hong Kong target tuberculosis

Published in TB and Outbreaks Week, April 8th, 2008

According to a study from Hong Kong, People's Republic of China, "Susceptibility to tuberculosis (TB) may be affected by host genetic factors. Elevated levels of transforming growth factor-beta I (TGF-beta(1)) were found in plasma of patients with active TB compared with those of healthy contacts."

"To investigate the association of TGF-beta(1) gene polymorphisms (C-509T and T869C) and plasma levels with the risk of TB in Hong Kong Chinese adults, a case-control study was carried out on 174 active TB patients and 174 healthy controls matched for age, gender and smoking. Blood samples from 180 blood donors served as another control group. Genotyping was carried out on...

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Source: TB and Outbreaks Week (2008-04-08)

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