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TB & Outbreaks Week

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Corynebacterium



Study findings on Corynebacterium are outlined in reports from H. Ogino and colleagues



April 8th, 2008

"DNA damage-induced SOS response elicits the induction of cell-division suppressor as well as DNA repair genes. In Gram-positive bacteria, cell-division suppressor genes, so far characterized from Bacillus subtilis (yneA) and Mycobacterium tuberculosis (rv2719c), share limited homology, but are both located in the vicinity of lexA on their respective genomes," researchers in Kyoto, Japan report.

"Using this proximity to lexA, Corynebacterium glutamicum R divS (cgR1759) was identified as an SOS-inducible cell-division suppressor in this study. The amino acid sequence of DivS showed no homology to that of YneA and Rv2719c. divS expression was markedly induced by...


Source: TB & Outbreaks Week (2008-04-08)

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