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TB & Outbreaks Week

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Drug Resistance



New drug resistance study findings have been reported from University of Edinburgh



April 15th, 2008

In this recent report, researchers in Scotland conducted a study "To detect genes conferring resistance to biguanides, quaternary ammonium compounds, beta-lactams and fluoroquinolones in clinical methicillin-resistant Staphylococcus aureus (MRSA) and to demonstrate whether reduced susceptibility is spread clonally and if the presence of any of the detected genes links to a specific epidemic MRSA. Finally, to identify if exposure to chlorhexidine may cause reduced susceptibility to antibiotics and chlorhexidine."

"In total, 120 clinical MRSA isolates were isolated. qacA/B, qacG, qacH, norA, smr and blaZ genes were amplified by PCR. MICs of eight antibiotics were...


Source: TB & Outbreaks Week (2008-04-15)

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