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TB & Outbreaks Week

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Biochemistry



Researchers' work from University of Wisconsin, Department of Biochemistry focuses on biochemistry



April 15th, 2008

Data detailed in 'GDP-perosamine synthase: structural analysis and production of a novel trideoxysugar' have been presented. According to recent research from the United States, "Perosamine or 4-amino-4,6-dideoxy-d-mannose is an unusual sugar found in the O-antigens of some Gram-negative bacteria such as Vibrio cholerae O1 (the causative agent of cholera) or Escherichia coli O157:H7 (the leading cause of food-borne illnesses). It and similar deoxysugars are added to the O-antigens of bacteria via the action of glycosyltransferases that employ nucleotide-linked sugars as their substrates."

"The focus of this report is GDP-perosamine synthase, a...


Source: TB & Outbreaks Week (2008-04-15)

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