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Coronavirus
Investigators at Pfizer Inc. publish new data on coronavirus
April 15th, 2008
Research findings, 'Steady-state and pre-steady-state kinetic evaluation of severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro cysteine protease: development of an ion-pair model for catalysis,' are discussed in a new report. According to recent research from the United States, "Severe acute respiratory syndrome (SARS) was a worldwide epidemic caused by a coronavirus that has a cysteine protease (3CLpro) essential to its life cycle. Steady-state and pre-steady-state kinetic methods were used with highly active 3CLpro to characterize the reaction mechanism." "We show that 3CLpro has mechanistic features common and disparate to the archetypical proteases...
Source: TB & Outbreaks Week (2008-04-15)
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