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TB & Outbreaks Week

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Crohn Disease



Researchers from Montreal General Hospital describe findings in Crohn disease



April 15th, 2008

According to recent research published in the journal Microbes and Infection, "Studies seeking Mycobacterium avium subsp. paratuberculosis in Crohn's disease by PCR have generated inconsistent findings. As an alternative, microscopy offers a number of advantages, including direct visualization of organisms in tissue."

"Experimental infections have demonstrated that M. avium organisms can be seen by both acid-fast staining and species-specific in situ hybridization, but because they are smaller than M. tuberculosis, oil-immersion microscopy (x 1000 magnification) is needed. We performed a blinded search for M. avium in paraffinembedded surgical resections from...


Source: TB & Outbreaks Week (2008-04-15)

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