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TB & Outbreaks Week

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Influenza



Studies from C.S. Cheng et al add new findings in the area of influenza



April 22nd, 2008

According to a study from Beijing, People's Republic of China, "New therapeutics are urgently needed for the treatment of pandemic influenza caused by H5N1 influenza virus mutants. Aptamer was a promising candidate for treatment and prophylaxis of influenza virus infections."

"In this study, systemic evolution of ligands through exponential enrichment (SELEX) was used to screen DNA aptamers targeted to recombinant HA1 proteins of the H5N1 influenza virus. After 11 rounds of selection, DNA aptamers that bind to the HA1 protein were isolated and shown to have different binding capacities. Among them, aptamer 10 had the strongest binding to the HA1 protein, and had an...


Source: TB & Outbreaks Week (2008-04-22)

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