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Legionnaire Disease
Researchers from Northwestern University, Medical Department detail findings in legionnaire disease
April 22nd, 2008
"Several Legionella pneumophila proteins were highly expressed in low-temperature supernatants," scientists writing in the journal Applied and Environmental Microbiology report. "One of these proteins was the peptidyl-prolyl isomerase PpiB," wrote M.A. Soderberg and colleagues, Northwestern University, Medical Department. The researchers concluded: "Mutants lacking ppiB exhibited reduced growth at 17 degrees C. Since PpiB lacked a signal sequence and was present in 17 degrees C supernatants of type II and type IV secretion mutants, this protein may be secreted by a novel mechanism." Soderberg and colleagues published their...
Source: TB & Outbreaks Week (2008-04-22)
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