Leishmaniasis

Studies from N. Singh and co-researchers yield new data on leishmaniasis

Published in TB and Outbreaks Week, April 22nd, 2008

According to recent research from Lucknow, India, "The chemotherapeutic interventions against visceral leishmaniasis (VL) are limited and facing serious concerns of toxicity, high cost, and emerging drug resistance. There is a greater interest in new drug developments from traditionally used medicinal plants which offers unprecedented diversity in structures and bioactivity."

"With this rationale, ethanolic extract of Tinospora sinensis Linn and its four fractions were tested in vitro against promastigotes and intracellular amastigotes and in vivo in Leishmania donovani infected hamsters. Ethanolic extract exhibited an appreciable activity against promastigotes (IC50...

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Source: TB and Outbreaks Week (2008-04-22)

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