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Infectious Disease
New infectious disease study findings have been reported by scientists at National Cheng-Kung University, Medical Department
April 29th, 2008
According to a study from Tainan, Taiwan, "Enterovirus 71 (EV71) causes fatal encephalitis in young children. However, there is no effective antiviral drug available for infected patients." "Ribavirin is currently used for the treatment of several RNA virus infections clinically, so its anti-EV71 efficacy was evaluated. In vitro results showed that ribavirin effectively reduced the viral yields (with an IC50 of 65 mu g/mL) and virus-induced cytopathic effect in human and mouse cell lines. In vivo results showed that ribavirin reduced the mortality, morbidity, and subsequent paralysis sequelae in infected mice by decreasing viral loads in tissues," wrote Z.H. Li and...
Source: TB & Outbreaks Week (2008-04-29)
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