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TB & Outbreaks Week

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Escherichia Coli



Reports summarize Escherichia coli study results from University of Birmingham



May 6th, 2008

"Bacteria contain a single multisubunit RNA polymerase that is responsible for the synthesis of all RNA," scientists in Birmingham, the United Kingdom report.

"Previous studies of the Escherichia coli K-12 laboratory strain identified a group of effector proteins that interact directly with RNA polymerase to modulate the efficiency of transcription initiation, elongation, or termination. Here we used a rapid affinity isolation technique to isolate RNA polymerase from the pathogenic Escherichia coli strain 0157:H7 Sakai," wrote D.J. Lee and colleagues, University of Birmingham.

The researchers concluded: "We analyzed the RNA polymerase enzyme complex...


Source: TB & Outbreaks Week (2008-05-06)

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