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TB & Outbreaks Week

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Leishmaniasis



Research from M.G. Tektonidou and co-researchers yields new findings on leishmaniasis



May 6th, 2008

"Tumor necrosis factor (TNF) is a proinflammatory cytokine that plays a key role in the pathogenesis of autoimmune diseases and is an important constituent of the human immune response to infection. We report the case of a 45-year-old man with psoriatic arthritis, receiving treatment with infliximab, who presented with high-grade fever, rigor, splenomegaly, acute reactive proteins, and pancytopenia," investigators in Athens, Greece report.

"The diagnosis of visceral leishmaniasis was established. The patient reported that his dog died from Leishmania infection 5 years ago, while he was living in an area endemic for Leishmania. The use of anti-TNF biologic agent in this...


Source: TB & Outbreaks Week (2008-05-06)

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