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TB & Outbreaks Week

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Tuberculosis



Studies from University of Hyderabad have provided new information about tuberculosis



May 6th, 2008

"cAMP Receptor Protein (CRP)/Fumarate Nitrate Reductase Regulator (FNR) family proteins are ubiquitous regulators of cell stress in eubacteria. These proteins are commonly associated with maintenance of intracellular oxygen levels, redox-state, oxidative and nitrosative stresses, and extreme temperature conditions by regulating expression of target genes that contain regulatory cognate DNA elements," scientists writing in the journal Gene report.

"We describe the use of informatics enabled comparative genomics to identify novel genes under the control of CRP regulator in Mycobacterium tuberculosis (M.tb). An inventory of CRP regulated genes and their operon...


Source: TB & Outbreaks Week (2008-05-06)

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