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Smallpox Vaccines
Reports outline smallpox vaccines study results from A. Ferrierrembert et al
May 13th, 2008
"This study assessed three non-replicating smallpox vaccine candidates (modified vaccinia Ankara (MVA), NYVAC and HR) for their immunogenicity and ability to protect mice against an intranasal cowpox virus challenge and compared them with the traditional. replicating vaccine," researchers in Grenoble, France report. "A single immunisation with the non-replicating vaccines induced a complete protection from death at short-term, but was not fully protective when mice were challenged 150 days post-vaccination with protection correlated with the specific neutralizing antibodies and CD4(+) T-cells responses. Prime-boost vaccination enabled effective long-term protection from...
Source: TB & Outbreaks Week (2008-05-13)
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