TB & Outbreaks Week
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Tuberculosis
Researchers at New York University target tuberculosis
May 13th, 2008
According to recent research from the United States, "Reactivation of Mycobacterium tuberculosis (TB) is a significant problem with all available tumour necrosis factor (TNF) antagonists when used to treat rheumatoid arthritis (RA), psoriatic arthritis, psoriasis and other inflammatory diseases. Concerns have been raised regarding the appropriate management of patients with latent TB (LTB) exposure (or active TB infection) before initiating TNF antagonists as the safety data of combined treatment with two potentially hepatotoxic medications, methotrexate (MTX) and isoniazid (INH), is lacking." "The goal of this study was to investigate the toxicity of MTX and INH...
Source: TB & Outbreaks Week (2008-05-13)
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