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Immunization
Study results from Columbia University update understanding of immunization
May 13th, 2008
Research findings, 'Use of an interferon-gamma release assay to diagnose latent tuberculosis infection in foreign-born patients,' are discussed in a new report. According to a study from the United States, "The tuberculin skin test (TST) has a low specificity in the setting of bacille Calmette-Guérin (BCG) vaccination. Interferon-gamma release assays (IGRAs) appear to be more specific but have not been validated in this population under routine clinical conditions." "We sought to validate the routine clinical use of the T-SPOT.TB test (Oxford Immunotec; Oxford, UK), an IGRA, in a predominantly foreign-born population with a high rate of BCG vaccination. We compared the...
Source: TB & Outbreaks Week (2008-05-13)
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