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Neuroblastoma Gene Therapy



Research on neuroblastoma gene therapy described by scientists at University of Hawaii, Department of Public Health Sciences



May 13th, 2008

Fresh data on neuroblastoma are presented in the report 'Inhibition of West Nile Virus replication by retrovirus-delivered small interfering RNA in human neuroblastoma cells.' "West Nile virus (WNV) has been responsible for the largest outbreaks of arboviral encephalitis in U.S. history. No specific drug is currently available for the effective treatment of WNV infection," scientists writing in the Journal of Medical Virology report.

"To exploit RNA interference as a potential therapeutic approach, a Moloney murine leukemia virus-based retrovirus vector was used to effectively deliver WNV-specific small interfering RNA (siRNA) into human neuroblastoma HTB-11...


Source: TB & Outbreaks Week (2008-05-13)

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