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TB & Outbreaks Week

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Heart Disease



Findings in heart disease reported from M.I. Azambuja and co-researchers



May 20th, 2008

According to a study from Porto Alegre, Brazil, "This essay proposes that the ecologic association shown between the 20th century coronary heart disease epidemic and the 1918 influenza pandemic could shed light on the mechanism associated with the high lethality of the latter."

"It suggests that an autoimmune interference at the apoB-LDL interface could explain both hypercholesterolemia and inflammation (through interference with the cellular metabolism of arachidonic acid). Autoimmune inflammation, then, would explain the 1950s-60s acute coronary events (coronary thrombosis upon influenza re-infection) and the respiratory failure seen among young adults in 1918," wrote...


Source: TB & Outbreaks Week (2008-05-20)

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