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TB & Outbreaks Week

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C Reactive Protein



Research conducted at University of Surrey has provided new information about c reactive protein



May 27th, 2008

According to a study from Guildford, the United Kingdom, "Neisseria meningitidis is a global cause of meningitis and septicemia. Immunity to N. meningitidis involves both innate and specific mechanisms with killing by serum bactericidal activity and phagocytic cells. C-reactive protein (CRP) is an acute-phase serum protein that has been shown to help protect the host from several bacterial pathogens, which it recognizes by binding to phosphorylcholine (PC) on their surfaces."

"Pathogenic Neisseria species can exhibit phase-variable PC modification on type I and 2 pili. We have shown that CRP can bind to piliated meningococci in a classical calcium-dependent manner. The...


Source: TB & Outbreaks Week (2008-05-27)

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