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HIV/AIDS Co-Infection
Study findings from D. Tan et al broaden understanding of HIV/AIDS co-infection
May 27th, 2008
"Objectives A proportion of HIV patients beginning antiretroviral therapy (ART) develop immune restoration disease (IRD). Immunological characteristics of IRD were investigated in a cohort of HIV patients beginning therapy in Kuala Lumpur, Malaysia," scientists in Perth, Australia report. " Peripheral blood mononuclear cells were collected at weeks 0, 6, 12, 24 and 48 of ART from five patients experiencing IRD [two with cryptococcal and three with Mycobacterium tuberculosis (Mtb) disease], eight non-IRD controls who had begun ART with CD4 T-cell counts of < 100 cells/mu L and 17 healthy controls. Leukocytes producing interferon-gamma (IFN gamma) were quantified by...
Source: TB & Outbreaks Week (2008-05-27)
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