TB & Outbreaks Week
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Influenza
Research from Boston University has provided new information about influenza
May 27th, 2008
"The influenza virus subtype H5N1 has raised concerns of a possible human pandemic threat because of its high virulence and mutation rate Although several approved anti-influenza drugs effectively target the neuraminidase, some strains have already acquired resistance to the currently available anti-influenza drugs. In this study, we present the synergistic application of extended explicit solvent molecular dynamics (MID) and computational solvent mapping (CS-Map) to identify putative 'hot spots' within flexible binding regions of N1 neuraminidase," investigators in the United States report. "Using representative conformations of the N1 binding region extracted from a...
Source: TB & Outbreaks Week (2008-05-27)
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