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Life Sciences
Findings from M.C. Monteiro et al in life sciences reported
May 27th, 2008
"Leishmania amazonensis infection leads to progressive diseases in a majority of inbred strains of mice. Glutathione (GSH) participates in a large number of cellular phenomena and seems to be essential for several immune functions, including host defense during leishmaniasis," scientists writing in the journal Parasitology Research report. "In this study, we evaluated the effects of N-acetyl-L-cysteine (NAC), as GSH supplement, on the course of L. amazonensis infection in susceptible BALB/c mice. The treatment with NAC (200 mg/kg daily) was effective in raising GSH levels in both lymph node and spleen cells. Although this treatment did not change the footpad...
Source: TB & Outbreaks Week (2008-05-27)
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