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TB & Outbreaks Week

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Neutropenia



Research from Erasmus University reveals new findings on neutropenia



May 27th, 2008

According to a study from Rotterdam, Netherlands, "Invasive pulmonary aspergillosis ( IPA) is a significant problem in patients with chemotherapy-induced prolonged neutropenia. Because pulmonary deposition of conidia is the first step in developing IPA, we hypothesized that inhalation of liposomal amphotericin B would prevent IPA."

"We performed a randomized, placebo- controlled trial of patients with hematologic disease with expected neutropenia for >= 10 days. Patients were randomized to receive liposomal amphotericin B or placebo inhalation twice a week, using an adaptive aerosol delivery system, until neutrophil counts increased to >300 cells/ mm(3). In...


Source: TB & Outbreaks Week (2008-05-27)

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