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TB & Outbreaks Week

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Protease



Researchers at University of Texas have published new data on protease



May 27th, 2008

"This paper reports a study to find small peptide substrates for the important virulence factor of Yersinia pestis, plasminogen activator, Pla," researchers in the United States report.

"The method used to find small substrates for this protease is reported along with studies examining the ability of these peptides to inhibit activity of the enzyme," wrote A. Agarkov and colleagues, University of Texas.

The researchers concluded: "Through the use of parallel synthesis and positional scanning, small tripeptides were identified that are viable substrates for the protease."

Agarkov and colleagues published their study in...


Source: TB & Outbreaks Week (2008-05-27)

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