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TB & Outbreaks Week

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Infectious Disease



Reports summarize infectious disease study results from University of Nottingham



June 3rd, 2008

"Increasing immunological dysfunction (atopy and autoimmunity) in western society may be linked to changes in undetermined environmental agents. We hypothesize that increased exposure to multiple gut worm species promotes stronger immunological regulation," researchers in Nottingham, the United Kingdom report.

"We report here that African children constitutively secrete more immunoregulatory cytokines (interleukin [IL]-10 and transforming growth factor [TGF]-beta 1) under conditions of hyperendemic exposure to the intestinal nematodes Ascaris lumbricoides and Trichuris trichiura, compared with conditions of mesoendemic exposure. Under conditions of hyperendemic...


Source: TB & Outbreaks Week (2008-06-03)

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