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TB & Outbreaks Week

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Influenza



Research on influenza described by scientists at Chinese University of Hong Kong



June 3rd, 2008

According to recent research from Hong Kong, People's Republic of China, "Avian H5N1 influenza virus causes a remarkably severe disease in humans, with an overall case fatality rate of greater than 50%. Human influenza A viruses induce apoptosis in infected cells, which can lead to organ dysfunction."

"To verify the role of H5N1-encoded NS1 in inducing apoptosis, the NS1 gene was cloned and expressed in human airway epithelial cells (NCI-H292 cells). The apoptotic events posttransfection were examined by a terminal deoxynucleotidyltransferase-mediated dUTP-biotin nick-end-labeling assay, How cytometric measurement of propidium iodide, annexin V staining, and Western...


Source: TB & Outbreaks Week (2008-06-03)

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