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Life Sciences
Researchers at McGill University have published new data on life sciences
June 3rd, 2008
According to recent research published in the Journal of Bacteriology, "Previous studies have established that members of the Mycobacterium tuberculosis complex exhibit variable production of the antigenic proteins MPT70 and MPT83 due to mutations in their positive regulator, SigK (sigma factor K), and their negative regulator, RskA (regulator of sigma K). To further understand this highly specific SigK-controlled regulon, we have undertaken evolutionary studies to determine the presence of homologues of SigK-regulated genes in other organisms and to predict its transcriptional network." "Evolutionary analysis indicates that the positive and negative regulators...
Source: TB & Outbreaks Week (2008-06-03)
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