TB & Outbreaks Week
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of TB & Outbreaks Week
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Tuberculosis
Research from Kyushu University in the area of tuberculosis described
June 3rd, 2008
"Protection against Mycobacterium tuberculosis not only depends on CD4(+) T helper type 1 (Th1) cells but, also, on CD8(+) T cells. Interleukin (IL)-15 has an important function in the maintenance of memory CD8(+) T cells," investigators in Fukuoka, Japan report. "In the present study, we examined the efficacy of recombinant Mycobacterium bovis bacille Calmette-Guerin (rBCG) secreting fusion protein antigen (Ag) 85B murine IL-15 (rBCG-Ag85B-IL15) in providing protection against M. tuberculosis infection. The levels of major histocompatibility (MHC) class Ib (H2-M3)-binding TB2- or MHC class Ia (H-2D(b))-binding MPT64-specific CD8(+) T cells producing interferon...
Source: TB & Outbreaks Week (2008-06-03)
|
