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TB & Outbreaks Week

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Vaccines



Research on vaccines published by N.A. Parlane et al



June 3rd, 2008

"The development of defined sub-unit vaccines requires the inclusion in the vaccine of an immunological adjuvant. The most important property of adjuvants for vaccines aimed at inducing optimal protection against intracellular bacteria such as Mycobacterium tuberculosis or M. bovis is the ability to enhance cell-mediated immunity, specifically Th1 responses," scientists in Palmerston North, New Zealand report.

"In this paper, we describe a system where transgenic mice expressing a high proportion of T cells specific for an ovalbumin (OVA) peptide are used to assess the ability of a novel class of adjuvants to positively modulate cell-mediated immune responses. Defined...


Source: TB & Outbreaks Week (2008-06-03)

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