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TB & Outbreaks Week

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University of British Columbia



Vancouver researchers discover missing link between TB bacteria and humans



June 10th, 2008

Researchers at the University of British Columbia and Vancouver Coastal Health Research Institute have discovered how tuberculosis (TB) bacteria hide and multiply in the human body and are working toward a treatment to block this mechanism of infection.

This discovery, published in the journal Cell Host and Microbe, describes the missing link between a TB protein and its newly discovered counterpart protein in the human body's white blood cells (macrophages).

TB causes disease by infecting the body's macrophages. Normally, macrophages engulf bacteria and then release powerful digestive enzymes that destroy the bacteria. The researchers found that a...


Source: TB & Outbreaks Week (2008-06-10)

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