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Tuberculosis
Recent findings in tuberculosis described by researchers from PPD Inc.
June 10th, 2008
According to recent research published in the journal Arthritis and Rheumatism, "Tumor necrosis factor (TNF) blockade increases the risk of tuberculosis (TB). The purpose of this study was to use Markov modeling to examine the contributions of reactivation of latent tuberculous infection (LTBI) and the progression of new infection with Mycobacterium tuberculosis to active TB due to TNF blockade." "These 2 pathogenic mechanisms cannot otherwise be readily distinguished. Monte Carlo simulation was used to represent the range of reported values for the incidence of TB associated with infliximab (TNF monoclonal antibody) and etanercept (soluble TNF receptor) therapy....
Source: TB & Outbreaks Week (2008-06-10)
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