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Hantavirus Animal Studies
New hantavirus animal studies findings from Johns Hopkins University published
June 10th, 2008
Data detailed in 'Seoul virus enhances regulatory and reduces proinflammatory responses in male Norway rats' have been presented. "Zoonotic pathogens, including hantaviruses, are maintained in the environment by causing persistent infection in the absence of disease in their reservoir hosts. Spillover of hantaviruses to humans can cause severe disease that is mediated by excessive proinflammatory responses," scientists in the United States report. "The mechanisms mediating hantaviral persistence in rodent reservoirs remain largely unknown. Male Norway rats were inoculated with their species-specific hantavirus, Seoul virus (SEOV), and viral RNA, cytokine, and chemokine...
Source: TB & Outbreaks Week (2008-06-10)
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