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TB & Outbreaks Week

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Immunology



Scientists at Montana State University, Department of Microbiology publish new data on immunology



June 10th, 2008

Research findings, 'Reduced nicotinamide adenine dinucleotide phosphate oxidase-independent resistance to Aspergillus fumigatus in alveolar macrophages,' are discussed in a new report. "The fungal pathogen Aspergillus fumigatus is responsible for increasing numbers of fatal infections in immune-compromised humans. Alveolar macrophages (AM) are important in the innate defense against aspergillosis, but little is known about their molecular responses to fungal conidia in vivo," scientists in the United States report.

"We examined transcriptional changes and superoxide release by AM from C57BL/6 and gp91(phox)(-/-) mice in response to conidia. Following introduction...


Source: TB & Outbreaks Week (2008-06-10)

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