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TB & Outbreaks Week

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Escherichia coli



Data on Escherichia coli published by researchers at Novartis



June 17th, 2008

According to recent research from Siena, Italy, "Extraintestinal pathogenic Escherichia coli are the cause of a diverse spectrum of invasive infections in humans and animals, leading to urinary tract infections, meningitis, or septicemia. In this study, we focused our attention on the identification of the outer membrane proteins of the pathogen in consideration of their important biological role and of their use as potential targets for prophylactic and therapeutic interventions."

"To this aim, we generated a Delta tolR mutant of the pathogenic IHE3034 strain that spontaneously released a large quantity of outer membrane vesicles in the culture supernatant. The...


Source: TB & Outbreaks Week (2008-06-17)

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