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TB & Outbreaks Week

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Neutropenia



Studies from O. Penack and colleagues reveal new findings on neutropenia



June 17th, 2008

"We carried out a prospective study on galactomannan enzyme immuno assay ( GEI) ( Platelia (TM) Aspergillus EIA, Bio- Rad) testing for diagnosis of invasive aspergillosis ( IA) in serum and broncho- alveolar lavage ( BAL) in 200 patients with hematological malignancies and profound neutropenia. The incidence of proven and probable IA was 6% and 5.5%, respectively," investigators in Berlin, Germany report.

"In patients with fever or pneumonia, a single- positive GEI test result ( galactomannan index >= 0.5) had excellent specificity ( 100%). Sensitivity was relatively low ( 40%) at onset of fever, but increased to 94.7% after 6 days of fever. In patients with...


Source: TB & Outbreaks Week (2008-06-17)

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