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TB & Outbreaks Week

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Smallpox Vaccines



Reports on smallpox vaccines findings from M.R.E.I. Benhnia and co-researchers provide new insights



June 17th, 2008

"The smallpox vaccine is widely considered the gold standard for human vaccines, yet the key antibody targets in humans remain unclear. We endeavored to identify a stereotypic, dominant, mature virion (MV) neutralizing antibody target in humans which could be used as a diagnostic serological marker of protective Immoral immunity induced by the smallpox vaccine (vaccinia virus [VACV])," scientists in the United States report.

"We have instead found that diversity is a defining characteristic of the human antibody response to the smallpox vaccine. We show that H3 is the most immunodominant VACV neutralizing antibody target, as determined by correlation analysis of...


Source: TB & Outbreaks Week (2008-06-17)

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