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TB & Outbreaks Week

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Tuberculosis



Data on tuberculosis described by M.G.A. Smitvandixhoorn et al



June 17th, 2008

According to recent research published in the journal Molecular Immunology, "Mycobacterium tuberculosis (M.tb) infects 8 million and kills 2.2 million people each year worldwide. M.tb modulates the immune response of the infected individual."

"Empirically, suppressor carbohydrates (SC) produced by CD8+ T cells in response to M.tb were found to induce a T helper 2 response rather than a protective T helper I response in human mononuclear (MN) cells. This study (1) identifies the genes that modulate the T helper response, (2) describes their function, and (3) postulates a detailed model for the M.tb infection mechanism. MN cells from five healthy donors were pulsed...


Source: TB & Outbreaks Week (2008-06-17)

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