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Enzyme Research

Reports outline enzyme research study results from University of Sao Paulo

Published in TB and Outbreaks Week, June 17th, 2008

Data detailed in 'The effect of phospholipase A2 from Crotalus durissus collilineatus on Leishmania (Leishmania) amazonensis infection' have been presented. "In this study, the effect of phospholipase A2 (PLA2) derived from Crotalus durissus collilineatus was evaluated in vitro and in vivo on experimental cutaneous leishmaniasis. The promastigote and amastigote forms treated with PLA2 presented increased growth rate," scientists in Sao Paulo, Brazil report.

"In vivo studies showed that PLA2-treated Leishmania (Leishmania) amazonensis promastigotes increased the size of lesions in BALB/c mice, and histopathological analysis showed numerous necrotic regions presenting a...

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