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Life Sciences
Research from J.P. Iyer and co-authors reveals new findings on life sciences
June 24th, 2008
"Leishmania donovani, the causative agent of visceral leishmaniasis, uses a cascade of enzymes that include cytosolic tryparedoxin peroxidase (cTXNPx) for detoxification of peroxides, an event pivotal for survival of digenic parasites living in two disparate biological environments. In this study, we observed an increase in promastigote cTXNPx levels after exposure to H2O2 and this group did not show any cell death; however, exposure to a combination of H2O2 and nitric oxide resulted in significant reduction of cTXNPx levels accompanied by high cell death," scientists in New Delhi, India report. "The protective relationship between higher levels of cTXNPx and survival...
Source: TB & Outbreaks Week (2008-06-24)
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